Jennifer Doudna (UC Berkeley / HHMI): Genome Engineering with CRISPR-Cas9

I heard cleavage and instantly agreed it was an exciting finding.

Älä ole piilossa

Onko tämä se internet sivu jonne kirjoitan tilinumeron?😅

Jennifer DouDNA, of the genome engineering team, the last three letters of your last name are what you are using CRISPR CAS-9 for 🤩editing of the human genome, that sort of technology is what was used back in the days of Thoth, of Atlantis, many Egyptian pharaohs, & many Sumarians used as well as many of the peoples of Ubaid, also in Malta Greece Turkey & Siberia, & South America & India too. I have time to live longer & two pussy cats plus myself😹😹😹

Thank you for the post!

❤

no scientest is perfect only GOD IS PERFECT THE INVENTION THIS WOMAN IS DEMONS THIS INVENTION USE BY ELITE SO THAT CONTROL THE WORLD

Very nice 👍👍 mam

So we can alter and modify DNA. And use this technique against viruses and Cancer ( Tumors) . Brain Cancer. Inoperable Cancer. We can also sterilize Mosquitoes. No more itch, Malaria, Yellow Fever. No insect or animal's diet relies solely on Mosquitoes. They're a snack food.

Idk how the hell they stumbled onto this major breakthrough. How do you even study something that small.

Really very well explanation ♥️

But how does the bacteria identify the viral RNA/DNA in the first place?!

Feel great to hear it from the Nobel prize winner herself

Fantastic intelligent scientists…. doing wonderful work. Congratulations

I have a question. How do bacteria respond to the viruses (bacteriophages) that are infecting for the first time? Do bacteria use the same CRISPR-Cas9 system for it or they switch to other system, since there is not any viral sequence present in the CRISPR Sequence of bacteria.

Transcribed? What is the sequence?

I'm reading the book and it is GREAT: The Code Breaker by Walter Isaacson. A page turner for sure.

This technology is amazing.
As far as I'm concerned is being used in sickle cell anemia treatment, the results have been incredible good so far.

Thank you for explaining this system. Ivworked. In this same dept at Stanley hall in the lab across the phage lab, fifty years ago, exciting to see the advances in science and technology and how far we have come.

You observed that the CRISPR knock-out of protein X either promotes or represses RNA polymerase II transcription, depending on the gene. Which experiments would you carry out to reveal the mechanism for this differential activity?

Brilliant! Well done Jennifer! 👏🏽

J Doudna deserves another Nobel prize for her research on RNA. It's not unlikely to see that happening in the upcoming yeasrs.

STAGE next ABOVE: "Field operation 'division'", from Allopathy, whether Gene Trigger Engineering or Engineer is autonomous professionalism or subordinations of Allopathy is questionable. As there's an independent quality of classifying diseases are inbuilt in GeneOpathy quantity of classifying diseases can be taken into account in Gene Cut Evolution based on its evaluation by future💰✊

Perhaps, the Congressmen may carelessly pass a half baked medical bill that they're DNA Trigger Engineers can't be treated as physicians should obey Allopathy doctors who'll provide a lab room in their hospitals' corner.

Scope of an invention RESULTS in the FIELD OPERATION DIVISION ought to be BRIGHT

nice speech

I couldn't focus.. once I noticed the sibilant "s" in her speech, it was like fingernails on blackboard.. Will try again later (after I forget to notice it).

Spoiler: She won the 2020 Nobel Prize in Chemistry along with her collegue Emmanuelle Charpentier for CRISPER-CAS9 gene editing.

Cant believe I am listenning an explanation from a nobel prize!!

Awesome.Bravo!

Extraordinary findings are always out of answering basic questions. Just like this, the unknown repeating genes in bacteria, what are their function?

По настоящему удивительно, послушать рассказ об этой технологии от человека, непосредственно принимавшего участие в понимании её работы.)

Amazing level of understanding.

Horrible. Without regard to the numbers of people killed and injured being secretly experimented on and activating adenovirus. Horrible you dont present the FACTS about the Real purpose to the experimentation. Messing with the DNA when you really dont even know enough to be injuring healthy people.

And you find some academic bullies (some scientists) trying to be smart than Jennifer. Bragging about CRISPER-Cas9 as if the own it.

Hello 2056 !!! I know you will be checking this video as how all started. By the way, the pandemia wasn't as fun

I know these research breakthroughs show us the potential for beneficial methods in medicine and health. But could this be used for biological warfare?

"l o l" ... the woman who co-created-discovered the technology is more adept at describing it's functionality than many derivative videos I've seen on the net since.

... The Professor must be very proud that her work has ultimately led to the prospect of mRNA-vector Vaccines being able to end this terrible Pandemic very soon.

Hopefully the medical community will use this for the good of humanity. Currently I don't see that happening, as most mainstream medicine is a pill or a scalpel, as well as being for profit.

WOW she gave no credit to the man who discovered it - CRISPRs were first discovered in archaea (and later in bacteria) by Francisco Mojica, a scientist at the University of Alicante in Spain. He proposed that CRISPRs serve as part of the bacterial immune system, defending against invading viruses.

Jennifer DounDNA

I love Jennifer Doudna.

Так, редагування геному - це прорив в інженерній генетиці, але які нас чекають віддалені наслідки втручання в геном ще невідомі. Можна тільки прогнозувати, що стійкість редагованих генів до впливу мутаційних факторів буде невеликою і ,як результат, будемо мати зростання злоякісних новоутворень. Значно перспективнішим і безпечнішим шляхом є пошук засобів збільшення експресії генів.

We need a cure for HIV, there are almost 40 years of desert, people who got hurt looking for Love, people who struggle every day, don't restrict the cure, it's painful! we pay taxes we are professionals, parents children mothers grandparents, this is in the hands of science and government, science with genetic research, government accelerating authorization, and not favoring an industry that profits from suffering. YHWH Raphael aj help us. 2021. Shalom!

The plasmid has a known sequence. The CRISPR guide RNA is made with a sequence matching the known plasmid sequence. (let’s look at lane one; GFP1) The location is picked because of the GG, so it is somewhat but not completely arbitrary. The plasmid is incubated with GFP1 and a regular restriction endonuclease. The circular plasmid is now two pieces and the sizes, according to gel electrophoresis, match the expected sizes. The cut occurred where predicted. Is that right?

Human DNA is too complex if compared with Doudna's name and her discover.