Respiratory | Oxygen-Hemoglobin Dissociation Curve

I have to say professor zach murphy is the best teacher and the kindest teacher, he is not only good at teaching and explaining ideas, but also fun and interactive, I seriously don't have words to express my gratitude.

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I was forced to learn the oxyhemoglobin curve. At the beginning of learning, I had many questions. After reading for two days and watching a number of videos on it, it makes sense now. However, I still have one question. What is the purpose of the oxyhemoglobin dissociation curve that I need to know? What does it matter if the O2 saturation drops from 98% to the percentage remaining after discharge due to affinity. As long as the venous blood in the pulmonary circulation receives a full recharge of O2, all is well. Learning the curse of oxyhemoglobin dissociation is like learning the color, type, and consistency of feces to diagnose disease - useless. Today the poop is too dry, but tomorrow the poop is too loose because E.coli, what can knowing about the person's poop lead to the diagnoses of their health - nothing. As in the knowledge of oxyhemoglobin dissociation cure, too cold leads to right shit result in high affinity, so what? Put on a blanket - problem solved.

Of all the videos on oxyhemoglobin dissociation curve I have seen, this one explains it the best.

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who saw the pink and orange lines before Sir said

great work with your tutorials

Your videos are magic!!! I don’t know how you do it, but I always understand so much more after you explain it!!!! Thank you 😊

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Bro you made my life easier! THANK YOU.
I hope other teachers learn how to explain things like you do.
All the best

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Binging for my quiz❤

thank you so much for this very informative yet humorous video. you have helped me a lot. God bless you

Appreciate your videos and style: clear and friendly. One fundamental correction that should be made: % saturation is NOT "percentage of oxygen that's bound to haemoglobin". The percentage of oxygen that binds to Hb is constant, approximately 98%. Oxygen sat is the PERCENTAGE OF HAEMOGLOBIN bound TO OXYGEN. The two sentences sound similar. But, they are VERY different, and not just in an academic sense. E.g.: one could have nearly all of one's arterial oxygen bound to Hb - as stated, usually 98% is bound in arterial blood - but the total oxygen content [dissolved O2 + HbO2] of the blood could still be low, if, for instance, one was not producing enough Hb. And in that case, one would have trouble getting enough oxygen, even though the "percentage of oxygen bound to Hb" was high. Even though certain states can affect how Hb binds oxygen and hence oxygenation, it's not usually the percentage of oxygen that's bound that's the problem, but the percentage of Hb that's bound. Pulse oximeters also work by detecting the changes in the light reflected from RBCs which in turn depends on Hb saturation. So: O2 sats are NOT indicating % oxygen that is saturating Hb. It's the other way around, and a patient's vital signs for oxygen are based on % saturation of Hb. In any case: keep up the good work.