Krebs Cycle | Made Easy!

Your drawing is wrong. Pyruvate Dehydrogenase is on the inner side of the mitochondria, not in the cell cytoplasm. Pyruvate does not convert to Acetyl-CoA in the cytoplasm and then cross into the mitochondria. Thanks for screwing with my head. I had to go to 6 different web sites to triple check.

This is a cycle
So OAA turns into Citrate.
That step is not explained.
Yet great video

I always look for my favorite and Versatile Doc. Dr. Mike...

Thank you sir

Great lecture
4 NADH = 24. ( 2X4)= 8×3=24+ 4(2FADH)+ 2ATP...total 30 + 8 glycolysis = 38

Super helpful video (as are the others you've done about cellular respiration). Thanks! One question, though. My textbook says that "*after* moving into the mitochondrial matrix, the pyruvic acid (or pyruvate) is converted into a 2-carbon compound called Acetyl coenzyme A (Acetyl CoA)." Most other sources I'm finding say the same. However, if I understand correctly, this video is saying that this happens before moving into the mitochondria, and that the pyruvate molecule actually needs CoA to be able to cross the mitochondria membrane. I'm curious about this difference. Thanks.

Coming back to this video for the 1000th time cause i always forget and watch it again

the MOST helpful explanation of the the kreb's cycle! The explanation using the carbon atoms made this finally make sense for me! Thank you :)

Don't you produce 4 ATP in Glycolysis

Bro said everyone's favourite

lol its 1:44am and my exam is today 🤣

What would be the clinical consequences of inhibiting the enzyme iso-citrate Dehydrogenase?

Thank you ❤

only God can reward you Dr. The best explanation ❤

Quick question: isn’t the glucose to pyruvate conversion process an ATP-taker instead of an ATP-producer? If it’s not ATP, what facilitates this conversion? Thank you!

How much this guy benching?

Thanks for this amazing video

How in the world did the scientists figure all this stuff out? It's truly marvelous. Thanks for the B-complex heads-up! Maybe I'm missing something here, but are the phosphates lost or depleted in this process?

I like how he throws in how all this works on the macro scale.

Thank you so much for being such amazing teachers on here as well as your podcast! Would you consider doing a whole video on the PDH complex?

thank you doctor mike!

I hope my professors don't expect me to memorize everything about this 😅

Best krebs cycle explanation

Dr Mike you're the goat for saving me in ap bio . cheers 🙌

Midterm tomorrow, must learn

every time I watch this it makes more and more sense. Such a great explanation

Adding in the carbon diagram changes my understanding of the cycle completely. How simple yet effective!

"Everyone's favorite...." It wasn't until after I watched this video. Thank You, Dr. Mike! I am inspired to be like you someday

I love the video! I just have one question. What about reducing power? When NAD+ turns into NADH shouldn't a hydrogen atom be oxidized so that the NAD+ takes an electron and a neutral hydrogen atom attaches to the NAD+ to make NADH? I was just double-checking to get your response on the subject.

ur the most jacked biology teacher I love it

Aaaaaaand I FINALLY freaking understand it now!!!!
Your videos should be required lectures for our A&P/ biology/ science classes.
Better than any other “teaching” method in my classes. Thank you! 🙏

❤ Thanks, can you explain how to retain all needed elements and how to add them to the body

I would like to suggest a small correction in the 3rd reaction where iso-citrate should convert into oxalo succinate before alpha-ketoglutarate dehydrogenase

THANK YOU SO MUCH FOR MAKING THESE!!!

brilliant, just brilliant.

Thank you very much!
Very detailed and informative video, God Bless You

The Krebs Cycle is a topic that is loved 😍😍😍😍 by students from St Finians College Secondary School Mullingar Co Westmeath Ireland who do/did
LC Biology as a one Science Subject
or
BOTH
LC Biology
LC Chemistry
A teacher who teaches
JC Mathematics
JC Science
L Mathematics
LC Biology
LC Chemistry
will come and get a PERMANENT JOB in St Finians College Secondary School Mullingar Co Westmeath Ireland

Thank you for explaining the kreb cycle. I have mercury poisoning and figured out because I had no more citric acid in me my body goes into a metabolic acidosis and citric acid reversed this but now I am needing a lot of sugar to function which explains the glucose process in the krebs cycle.

Man I like your videos. They are great

Yoh

Thank you u real made biochem easy for me 🙏

ily

Fantastic work!!!! It helped a ton!

BRILLIANT! Thanks.

What about the Candle cycle and the use of fat rather than glucose on a Carnivore diet

All I get is that it’s good to eat eggs. Right? (B vits).

❤❤

My mind is completely blown. This is the best explanation of the krebs cycle I've seen. Thank you!

Fucking brilliant... I wish I had this 40-odd years ago when I did my biochem degree.... PS. I've forgotten almost EVERYTHING talked about in this video :-(

Thank you