New Isaac Content

The CREEPIEST Isaac Boss EVER! Cacophobia (Fiend Folio) 2:29
The CREEPIEST Isaac Boss EVER! Cacophobia (Fiend Folio) SlayXc2 2,292,225 1 год назад
Isaaconnect - A New Isaac Game! 5:04
Isaaconnect - A New Isaac Game! IsaacGuru 3,479 4 дня назад
I Turned Isaac INTO Getting Over It! It's Amazing! 36:55
I Turned Isaac INTO Getting Over It! It's Amazing! TheTurtleMelon 208 2 часа назад
The Binding of Isaac RUINED Video Games For Me... 12:40
The Binding of Isaac RUINED Video Games For Me... ZackLillipad 8,391 4 дня назад
ALL Unused Content in Isaac 9:01
ALL Unused Content in Isaac HAMAZIAD 61,135 8 месяцев назад
I Gave Isaac 64 Quad Shots. This Was The Result 12:31
I Gave Isaac 64 Quad Shots. This Was The Result lavencas 689,941 1 год назад
OMG I FINALLY SAW NEW ISAAC STUFF!!!1! 33:21
OMG I FINALLY SAW NEW ISAAC STUFF!!!1! YuB 265,065 2 года назад
All Enemies Showcase - The Binding of Isaac: WhyBirth (Mod) 6:05
All Enemies Showcase - The Binding of Isaac: WhyBirth (Mod) SlayXc2 240,668 3 года назад
If ISAAC was a PUZZLE ROGUELIKE! 44:29
If ISAAC was a PUZZLE ROGUELIKE! Milana 36 8 часов назад
Repentance's Unused Enemies | The Binding of Isaac: Repentance 5:36
Repentance's Unused Enemies | The Binding of Isaac: Repentance Grub 155,260 3 года назад
3 New *OFFICIAL* transformations in ISAAC! #tboi #tboirebirth #tboirepentance 0:34
3 New *OFFICIAL* transformations in ISAAC! #tboi #tboirebirth #tboirepentance Cooked Elk 11,583 2 дня назад
I Made a Quiz Where The Points Are Completely Random 1:02:29
I Made a Quiz Where The Points Are Completely Random ZaneGames 21,649 5 часов назад
Mom's Knife SPEEDRUN World Record 12:37
Mom's Knife SPEEDRUN World Record lavencas 1,299,705 1 год назад
The Fastest Gold Knife of ALL TIME 13:24
The Fastest Gold Knife of ALL TIME lavencas 304,957 1 год назад
I Got EVERY Checkmark in ONE RUN 25:50
I Got EVERY Checkmark in ONE RUN Lazy Mattman 711,493 1 год назад
Unused Achievements [Cut Content] - The Binding of Isaac Repentance 11:44
Unused Achievements [Cut Content] - The Binding of Isaac Repentance IsaacGuru 404,897 3 года назад
TOP 20 Most ANNOYING New Enemies in Repentance - The Binding of Isaac Repentance 18:32
TOP 20 Most ANNOYING New Enemies in Repentance - The Binding of Isaac Repentance IsaacGuru 256,094 3 года назад
The Cody Ko Situation Is Disgusting... 18:16
The Cody Ko Situation Is Disgusting... SomeOrdinaryGamers 54,518 1 час назад
How I Got Over 19 QUADRILLION DAMAGE 18:58
How I Got Over 19 QUADRILLION DAMAGE lavencas 717,224 1 год назад
I Downloaded 100+ Isaac Mods. This was the result. 21:21
I Downloaded 100+ Isaac Mods. This was the result. Lazy Mattman 246,225 7 месяцев назад
This Exploit Is SO MUCH Fun (Enjoy While It Lasts) 20:01
This Exploit Is SO MUCH Fun (Enjoy While It Lasts) lavencas 89,394 9 месяцев назад
Top 5 Easy Unlocks in The Binding of Isaac: Repentance 2:55
Top 5 Easy Unlocks in The Binding of Isaac: Repentance Delvegameguides 136,459 1 год назад
New MOTHER ENDING Cutscene - The Binding of Isaac Repentance 1:19
New MOTHER ENDING Cutscene - The Binding of Isaac Repentance IsaacGuru 1,474,523 3 года назад
New Beggars and Machines! - The Binding of Isaac: Repentance 6:05
New Beggars and Machines! - The Binding of Isaac: Repentance SlayXc2 429,838 3 года назад
Crying My Way Through New Content | Binding of Isaac: Repentance #2 31:47
Crying My Way Through New Content | Binding of Isaac: Repentance #2 Mr Samuel Streamer 18,280 3 года назад
My FIRST TIME Playing The Biggest Isaac Mod (Fiend Folio) 22:03
My FIRST TIME Playing The Biggest Isaac Mod (Fiend Folio) lavencas 172,786 1 год назад
The New Isaac Update is HUGE (Repentance v.1.9.7) 20:08
The New Isaac Update is HUGE (Repentance v.1.9.7) Lazy Mattman 179,835 6 месяцев назад
The Ultimate Guide to the Binding of Isaac: Path to Dead God 20:30
The Ultimate Guide to the Binding of Isaac: Path to Dead God Priets 1,121,642 2 года назад
The Binding of Isaac but it's Only Finding Secret Rooms... 37:14
The Binding of Isaac but it's Only Finding Secret Rooms... Olexa 14,969 2 дня назад
New Isaac Save File in 2024??? 20:13
New Isaac Save File in 2024??? Dan Gheesling 9,627 6 месяцев назад

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